TrialNet Research Leads to FDA Approval of First Drug to Delay Type 1 Diabetes
Media Release

TrialNet Research Leads to FDA Approval of First Drug to Delay Type 1 Diabetes

Landmark findings from TrialNet research were instrumental in the Food and Drug Administration’s (FDA) November 17, 2022 approval of the first drug to delay type 1 diabetes (T1D) in people at risk.

TrialNet conducted the clinical study that discovered the immunotherapy drug teplizumab could delay T1D for 2+ years.

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An illustration of TrialNet heroes Owen and Ella in a lab. Ella uses a tablet to plan a mission and pack supplies while Owen repairs knee armor on his red super suit.
Participant Spotlight

Meet TrialNet heroes: Owen and Ella

Meet Owen & Ella: As another modular plate locks into place Owen does a fist bump. Whenever he adds a new piece to enhance the armor on his super suit he loves making the pieces snap together, just like his favorite Legos. Always calm under pressure, Ella goes over detailed schematics for their next TrialNet T1D Heroes Academy mission.

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An illustration of TrialNet hero Orlando Brown, Jr. wearing a football uniform and holding up a round shield to deflect a lightning bolt
Participant Spotlight

Meet TrialNet hero: Orlando Brown, Jr.

Meet Orlando Brown, Jr.: You may recognize the Kansas City Chiefs offensive tackle, also known as “Zeus”. It’s evident why, especially on the gridiron. More than 350 pounds of superhuman muscle and momentum sprinting downfield, Orlando inherited the name and strength of his father, also an NFL hero.

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An illustration of TrialNet heroes Citlaly & Maria practicing water bending and disc throwing at the water fountains
Participant Spotlight

Meet TrialNet heroes: Citlaly and Maria

Meet Citlaly & Maria: Super siblings united! Wind and water follow their command as Citlaly and Maria roam through downtown San Jose. Citlaly’s frisbee whistles as it whips through the air in a long arc circling the skyscrapers. In between TrialNet T1D Heroes Academy missions and studying to be a nurse, Maria tests her ability to manipulate water from the city fountains.

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An illustration of TrialNet hero Lilah Montgomery dances on a stage in a blue dress and tights. Light sparks from Lilah's fingertips as she creates a winter wonderland.
Participant Spotlight

Meet TrialNet hero: Lilah Montgomery

Meet Lilah: Foggy vapors rise from Lilah's icy, curly tendrils and little puffs of smoke gather about her fingertips as she twirls in relevé. Lilah glides across the room smooth as ice during dance class and finds it easy to keep her nerves cool before recitals.

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An illustration of TrialNet hero Tim Garman flying in the air wearing a blue super suit and golden cape. Tim is holding out his award-winning cinnamon raisin bread to a child.
Participant Spotlight

Meet TrialNet hero: Tim Garman

Meet Tim: The smell of warm cinnamon and melted butter rises from Tim’s basket of award-winning cinnamon bread, wafting over northern California. He’s always ready to share a fresh-baked loaf before flying home to meet with his support group for families of children newly diagnosed with type 1 diabetes (T1D).

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An illustration of TrialNet heroes Talia and Ali in a treehouse lab staring at a screen projected from a tablet. Talia is standing while Ali is floating beside her.
Participant Spotlight

Meet TrialNet heroes: Talia and Ali

Meet Talia & Ali: Sisters Talia and Ali use their superhero powers to prevent health conditions from ending up as emergencies. Talia combines her health informatics skills with time travel to identify who’s headed for trouble. Ali jets through the clouds at superspeed to deliver the news.

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An illustration of TrialNet hero Luke Sorenson running fast on a dirt road wearing a cowboy hat and cape.
Participant Spotlight

Meet TrialNet hero: Luke Sorensen

Meet Luke: Puffs of dust swirl in a path around the barn. The chickens stir, ducks wobble forward, sheep bleat, and the pony snorts in response to a soft whoosh of air. It’s 8-year-old TrialNet hero Luke running at hyper speed to complete his chores before the start of the school day.

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