Pathway to Prevention

If you have a relative with T1D, you’re in a unique position to help us learn more about the disease and how to stop it. The first step is to sign up for Pathway to Prevention screening to determine your risk of developing T1D. 

Family members of people with T1D
Risk Screening
Currently Enrolling

About the Study

Study Details

Pathway to Prevention screening is the first step for all TrialNet prevention studies. Screening is offered free to relatives of people with T1D to evaluate their personal risk of developing the disease. This unique screening can identify the early stages of T1D years before any symptoms appear. It also helps researchers learn more about how T1D develops and plan new studies exploring ways to prevent it. 

•    Relatives of people with T1D are 15 times more likely to develop the disease than the general population. 
•    Increased risk of developing T1D is linked to the presence of five diabetes-related autoantibodies.
•    The JDRF, ADA and Endocrine Society now classify having two or more of these autoantibodies as early stage T1D

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Eligibility Requirements

Who can participate?

You qualify for free risk screening if you: 

•    are between the ages of 1 and 45 and have a parent, brother/sister, or child with T1D (ages 3-45 in the United Kingdom)
•    are between the ages of 1 and 20 and have an aunt/uncle, cousin, grandparent, niece/nephew, or half-brother/sister with T1D (ages 3-20 in the United Kingdom)
•    have not been diagnosed with diabetes

Participant Experience

What is required?

With the advanced screening offered in this study, you will learn if you are in the early stages of T1D. Almost all people who screen positive for two or more diabetes-related autoantibodies will develop T1D. Detecting the disease in its earliest stage gives you the opportunity to try to change the course of the disease. TrialNet offers clinical trials testing ways to slow or stop the disease at every stage. 

Screening is free, quick, convenient and super important. Only a small sample of blood (about half a teaspoon) is required. The sample can be collected at a TrialNet site or a lab near you. For children we use a numbing solution that makes it practically painless. Results are ready in 4-6 weeks.