Current Studies

Our studies for people newly diagnosed with T1D are testing ways to preserve insulin and slow down or stop disease progression.

Many people newly diagnosed are making some insulin. You may have heard this referred to as the “honeymoon phase.” The goal of our studies is to maintain insulin production for as long as possible. Research shows that maintaining insulin production results in fewer complications, better glucose control, and lower A1C levels. 

Tolerance Using Plasmid (TOPPLE) Study: Phase 1

TrialNet is testing the safety of a new treatment, NNC0361-0041, in adults diagnosed with type 1 diabetes (T1D) in the past 48 months. This is a Phase 1 study, which means it is the first time this treatment is being tested for safety in people. If this study results in no safety concerns, we plan to conduct a larger study to see if this same treatment can slow down or stop T1D in people at high risk, before clinical diagnosis. More