External shot of the Columbia University Russ Berrie Medical Science Pavilion

Columbia University is one of twenty-two type 1 diabetes TrialNet International Clinical Centers at the forefront of type 1 diabetes research. Led by Robin Goland, MD, the TrialNet team at Columbia University is dedicated to preventing type 1 diabetes and stopping disease progression by preserving insulin production before and after diagnosis.

Our Team

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Robin Goland, MD

Dr. Robin Goland, J. Merrill Eastman Professor of Clinical Diabetes, Professor of Medicine and Pediatrics at Columbia University, directs the patient care and clinical research programs at the Berrie Center. She was instrumental in establishing the Naomi Berrie Diabetes Center in July 1998. Under the leadership of Dr. Goland and Berrie Center Co-Director Dr. Rudolph Leibel, the Berrie Center has become recognized nationally and internationally for excellence and innovation in patient care and research in diabetes. Dr. Goland has a B.A. from Harvard University and an M.D. from Columbia University College of Physicians & Surgeons. She was a resident and chief medical resident at NY-Presbyterian Hospital and did her endocrinology research training at Columbia University.

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Magdalena Bogun, MD

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Kristen Williams, MD

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Rachelle Gandica, MD

Jamie Hyatt, RN, BSN, CDCES

Silpa Sharma

Lucia Alfano

James Pring

Regional Affiliates

Morristown Memorial Hospital
100 Madison Ave., Box 53 , Morristown, 07962 United States
The Childrens Hospital, Buffalo
219 Bryant St - Endocrinology , Buffalo, 14222 United States
Winthrop University Hospital
101 Mineola Blvd., 2nd Floor , Mineola, 11501 United States
University of Rochester
601 Elmwood Ave., Box 777, Room 4-5227 , Rochester, 14642 United States
Joslin Center at SUNY Upstate Medical University
505 Irving Ave. IHP Room 1232B , Syracuse, 13210 United States

Research Studies

Risk Screening Risk Screening for Relatives

If you have a relative with T1D, you may be eligible for risk screening that can detect the early stages of T1D years before symptoms appear. More

Monitoring Monitoring

Depending on your risk screening results, you may be eligible for monitoring. We’ll monitor you for disease progression and let you know if you become eligible for a study. More

Prevention Study Hydroxychloroquine (HCQ)

We are testing the drug hydroxychloroquine (HCQ) to see if it can delay or prevent early stage T1D (stage 1) from progressing to abnormal glucose tolerance (stage 2) and ultimately prevent clinical diagnosis (stage 3). HCQ is already used to reduce symptoms and progression of other autoimmune diseases, such as rheumatoid arthritis and lupus. This is the first study to see if it can prevent or delay T1D. Details

Prevention Study Abatacept Prevention Study

TrialNet tested the drug abatacept to see if it could delay or prevent stage 1 T1D (two or more diabetes-related autoantibodies, but normal blood sugar) from progressing to stage 2 (abnormal blood sugar) or to stage 3 (clinical diagnosis). In an earlier study in people newly diagnosed (stage 3), participants treated with abatacept had 59% better insulin production and a 9.6-month average delay in progression of insulin loss compared to those who received placebo. That difference extended out to 3 years. Details

Long Term Long-Term Follow-up

If you are diagnosed with T1D while participating in one of our prevention studies, we’re still here for you. You can continue to receive personal monitoring while helping us learn more. More

Newly Diagnosed Tolerance Using Plasmid (TOPPLE) Study: Phase 1

TrialNet is testing the safety of a new treatment, NNC0361-0041, in adults diagnosed with type 1 diabetes (T1D) in the past 48 months. This is a Phase 1 study, which means it is the first time this treatment is being tested for safety in people. If this study results in no safety concerns, we plan to conduct a larger study to see if this same treatment can slow down or stop T1D in people at high risk, before clinical diagnosis. More