Aerial view of University of Bristol

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The University of Bristol is one of twenty-two type 1 diabetes TrialNet International Clinical Centers at the forefront of type 1 diabetes research. Led by Yuk Fun-Liu, MD, the TrialNet team at University of Bristol is dedicated to preventing type 1 diabetes and stopping disease progression by preserving insulin production before and after diagnosis. 


Our Team

yuk fun liu

Yuk-Fun Liu, MD

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Beth Thorne

Clinical Trials Programme Manager
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Samantha Loud

Paediatric Research Nurse
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Pilar Munoz

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Tracey Hughes

Research Assistant Practitioner

Regional Affiliates

Affiliates provide opportunities for people who do not live near a TrialNet Clinical Center. The affiliate sites listed below work with University of Bristol to offer convenient participation in our research programs

Royal Belfast Hospital for Sick Children
180 Falls Rd. BT12 6BE , Belfast, BT12 6BE United Kingdom
Royal Devon and Exeter Hospital
Royal Devon and Exeter Hospital Barrack Road, Exeter, EX2 5DW United Kingdom
Royal Aberdeen Childrens Hospital
Royal Aberdeen Children's Hospital , Aberdeen, AB25 2ZG United Kingdom
Leicester Royal Infirmary
Leicester Royal Infirmary , Leicester, LE1 5WW United Kingdom
Alder Hey Childrens Hospital
E Prescot Rd , Liverpool, L14 5AB United Kingdom
Sheffield Children's Hospital
Sheffield Children's Hospital , Sheffield, S10 2TH United Kingdom
Harrogate District Hospital
Harrogate District Hospital , Harrogate, HG2 7SX United Kingdom
Nottingham University Hospital
Nottingham University Hospital , Nottingham, NG7 2UH United Kingdom
Hull Royal Infirmary
Hull Royal Infirmary , Hull, HU3 2JZ United Kingdom
Ormskirk and District General Hospital
Ormskirk and District General Hospital , Southport & Ormskirk, L39 2AZ United Kingdom

Research Studies

Monitoring Monitoring

Depending on your risk screening results, you may be eligible for monitoring. We’ll monitor you for disease progression and let you know if you become eligible for a study. More

Prevention Study Abatacept Prevention Study

TrialNet is testing the drug abatacept to see if it can delay or prevent progression of early stage T1D (stage 1 or stage 2), and ultimately prevent clinical diagnosis (stage 3). In earlier studies for people newly diagnosed (stage 3), abatacept helped slow down disease progression. Details

Prevention Study Hydroxychloroquine (HCQ)

We are testing the drug hydroxychloroquine (HCQ) to see if it can delay or prevent early stage T1D (stage 1) from progressing to abnormal glucose tolerance (stage 2) and ultimately prevent clinical diagnosis (stage 3). HCQ is already used to reduce symptoms and progression of other autoimmune diseases, such as rheumatoid arthritis and lupus. This is the first study to see if it can prevent or delay T1D. Details

Long Term Long-Term Follow-up

If you are diagnosed with T1D while participating in one of our prevention studies, we’re still here for you. You can continue to receive personal monitoring while helping us learn more. More

#T1DFamily Spotlight

Meet some of our TrialNet #T1DFamily members to learn what it’s like to participate in a TrialNet clinical research study.